Status:

COMPLETED

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Malignant Neoplasm

Eligibility:

All Genders

Up to 22 years

Phase:

PHASE2

Brief Summary

This randomized clinical trial studies local anesthetic (EMLA) cream in younger patients undergoing lumbar punctures (LP). A local anesthetic cream may be effective for numbing the skin and reducing m...

Detailed Description

PRIMARY OBJECTIVES: I. To determine whether the application of a topical anesthetic (EMLA cream) to the LP site will decrease the total dose of propofol administered to pediatric oncology patients wh...

Eligibility Criteria

Inclusion

  • Pediatric oncology patients undergoing a lumbar puncture in the Pediatric Sedation Suite; patients may or may not be receiving intrathecal chemotherapy

Exclusion

  • Patients undergoing additional procedures during the same anesthetic such as bone marrow aspirate or biopsy will be excluded because they will likely require higher doses of propofol than those undergoing LP alone Patients who are allergic to or not tolerant of EMLA cream, propofol, or fentanyl will be excluded Patients who are pregnant will be excluded Patients having their LPs done by students will be excluded

Key Trial Info

Start Date :

May 14 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 26 2018

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT01516684

Start Date

May 14 2012

End Date

June 26 2018

Last Update

September 6 2019

Active Locations (1)

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Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States, 27157