Status:
UNKNOWN
Exercise Training in Patients With Hypertrophic Cardiomyopathy
Lead Sponsor:
Sheba Medical Center
Conditions:
Hypertrophic Cardiomyopathy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Exercise training (ET) is highly beneficial in heart failure patients and has been suggested to confer significant symptomatic and functional improvements in patients with diastolic dysfunction. Accor...
Eligibility Criteria
Inclusion
- Hypertrophic Cardiomyopathy
- NYHA 3
- Maximal left ventricular wall thickness \> 20 mm
- Age \>18
Exclusion
- Severe non-cardiac limitations of functional capacity such as neurological illness, lung disease, peripheral vascular or orthopedic problem, etc.
- Patients state post resuscitation for malignant ventricular arrhythmia.
- History of effort induced syncope, complex ventricular arrhythmia or atrial fibrillation.
- An exercise-induced decrease in blood pressure
- Severe left ventricular outflow obstruction defined as resting outflow gradient \> 50 mmHg on maximal therapy
- Atrial fibrillation with a poorly controlled ventricular response
- Advanced hypokinetic stage of HCM defined as LVEF \< 40%
- Congestive heart failure of angina FC IV according to NYHA or CCS respectively.
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01518114
Start Date
December 1 2011
Last Update
January 31 2012
Active Locations (1)
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1
Sheba Medical Center
Tel Hashomer , Ramat Gan, Israel