Status:
COMPLETED
Multiple Sclerosis and Progressive Resistance Training
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
Aarhus University Hospital
Biogen
Conditions:
Multiple Sclerosis (Relapsing Remitting)
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate underlying mechanisms possibly explaining the beneficial effects of progressive resistance training for people with multiple sclerosis.
Detailed Description
Exercise in general, and progressive resistance training (PRT) in particular, is regarded as an important tool in the rehabilitation of people with multiple sclerosis (MS). Previous studies have repo...
Eligibility Criteria
Inclusion
- Diagnosed relapsing-remitting MS according to the McDonald criteria
- Expanded Disability Status Scale (EDSS) between 2.0 and 5.5
- Be able to train twice a week at the University
- Use interferon based medication
Exclusion
- Alcohol abuse, Alzheimer's and pacemaker (or other metallic implant)
- Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases
- Having had an attack in a period of 8 weeks prior to the start of the intervention period
- Having an attack during the intervention period
- Pregnancy
- Systematic resistance training in a period of 3 months prior to the start of the intervention period.
- Training adherence of less than 85%.
Key Trial Info
Start Date :
February 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT01518660
Start Date
February 1 2012
End Date
January 1 2014
Last Update
December 2 2014
Active Locations (2)
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1
MS Clinic, Department of Neurology, Aarhus University Hospital
Aarhus C, Denmark, 8000
2
Sport Science, Aarhus University
Aarhus C, Denmark, 8000