Status:
COMPLETED
Assessment Of Liver Function in Patients Undergoing Hepatic Irradiation
Lead Sponsor:
University of Michigan Rogel Cancer Center
Conditions:
Hepatic Irradiation
Eligibility:
All Genders
18+ years
Brief Summary
The goal of the trial is to assess the effect of radiation treatment on liver function as determined by indocyanine green extraction. The long term goal is to determine if individual assessment of liv...
Detailed Description
Following intravenous injection, IC-GREEN is rapidly bound to plasma protein, of which albumin is the principle carrier (95%). IC-GREEN is taken up from the plasma almost exclusively by the hepatic pa...
Eligibility Criteria
Inclusion
- 18 or older, all gender, ethnicities and races
- Life expectancy of at least 12 weeks
- Zubrod performance status ≤ 2
- Baseline clinical assessments of liver function by complete history and physical examination
- Laboratory tests to be done within 6 weeks prior to start of radiation: CBC and platelets, liver function tests including SGOT, SGPT, Alkaline Phosphatase, and bilirubin, albumin, BUN, creatinine, PT/PTT, INR
Exclusion
- Pregnant
- History of allergy or are sensitive to IC-Green, iodine or to radiographic media
Key Trial Info
Start Date :
November 24 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 19 2020
Estimated Enrollment :
208 Patients enrolled
Trial Details
Trial ID
NCT01519219
Start Date
November 24 2004
End Date
February 19 2020
Last Update
May 20 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States, 48109-5010