Status:

COMPLETED

Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension

Lead Sponsor:

Brigham and Women's Hospital

Conditions:

Intra-dialytic Hypotension

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Kidney failure can result from a variety of conditions and can be temporary or permanent. Hemodialysis is available as a replacement treatment to perform the work that the kidneys normally do. However...

Eligibility Criteria

Inclusion

  • Renal failure requiring intermittent hemodialysis initiation; adult patients aged over 18 years; written informed consent

Exclusion

  • Hyponatremia \<130 mmol/L; acute myocardial infarction or stroke in previous 7 days; cardiac transplant; ventricular arrhythmia; unstable angina; use of pressors/midodrine; enrollment in conflicting research study; institutionalized individuals; pregnancy; prisoners; documented allergy to mannitol

Key Trial Info

Start Date :

May 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2018

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT01520207

Start Date

May 1 2012

End Date

December 1 2018

Last Update

January 30 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115