Status:
COMPLETED
Implant Surface Decontamination in Peri-implantitis Treatment
Lead Sponsor:
University Medical Center Groningen
Conditions:
Peri-implantitis
Periodontal Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Peri-implantitis is an infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone. Because the number of implants placed in everyday clinical practi...
Eligibility Criteria
Inclusion
- The patient is ≥ 18 years of age
- The patient has at least one endosseous implant in the oral cavity with clinical and radiographical signs of peri-implantitis. Peri-implantitis is defined as a loss of marginal bone ≥ 2 mm as compared to a fixed reference point on the dental implant, in combination with bleeding and/or suppuration on probing and a peri-implant probing depth ≥ 5 mm;
- The implants have been exposed to the oral environment for at least two years;
- The patient is capable of understanding and giving informed consent.
Exclusion
- Medical and general contraindications for the surgical procedures;
- A history of local radiotherapy to the head and neck region;
- Pregnancy and lactation;
- Diabetes;
- Systemic use of antibiotics during the last 3 months;
- Long-term use of anti-inflammatory drugs;
- Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
- Active, uncontrolled periodontal pathology of the remaining dentition;
- Local use of antibiotics or use of other anti-septic / antimicrobial therapies in the oral cavity during the last 3 months;
- Use of mouthrinses;
- Bruxism;
- Implants placed in skin grafted areas;
- Implants with bone loss due to other reasons than bacterial infection (e.g. loose screw, inadequate positioning of the implant);
- Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
- Implant mobility;
- Implants at which no position can be identified where proper probing measurements can be performed;
- Previous surgical treatment of the peri-implantitis lesions;
- Previous non-surgical treatment of the peri-implantitis lesions during the last 6 months (scaling or curretage).
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01521260
Start Date
October 1 2009
End Date
September 1 2011
Last Update
April 18 2024
Active Locations (1)
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1
University Medical Center Groningen
Groningen, Netherlands, 9700RB