Status:

COMPLETED

Cryoballoon Pulmonary Venous Isolation in Patients Referred for Typical Atrial Flutter Ablation

Lead Sponsor:

University Hospital, Rouen

Collaborating Sponsors:

Medtronic

Conditions:

Atrial Flutter

Atrial Fibrillation

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

\- Background: Atrial fibrillation is frequently associated with typical atrial flutter in clinical practice. If the radical treatment of atrial flutter by radiofrequency catheter is achieved in most...

Eligibility Criteria

Inclusion

  • Patient with a spontaneous flutter or with a flutter recurrence when it was not considered appropriate to use a preventive treatment so far. The flutter may have been paroxysmal or may still be present.
  • Patient with at least one documented episode of typical flutter defined as follows: negative F waves in the inferior territory, positive in V1 and negative in V6 lead, F wave pattern with characteristic "saw tooth" appearance and finally a heart rate comprised between 240 and 320 beats per minute.
  • Patient with effective anticoagulant therapy for at least 3 weeks.
  • Patient with at least one episode of AF (lasting more than 1 minute) documented on an ECG or a 24 hour Holter recording
  • Patient who signed an informed consent.
  • Patient with age ≥ 18 yo and ≤ 75 yo

Exclusion

  • Patients with the following characteristics will be excluded:
  • Contraindication to right-heart catheterization
  • Contraindication to an anticoagulant treatment
  • Patient for which AF is predominant (more recordings of AF than Flutter)
  • Persistent AF at the time of inclusion visit
  • History of mitral valve surgery
  • Known disorders of blood clotting
  • Cardiothyreosis
  • Life expectancy \< 24 months
  • Less than 18 years old and pregnant ladies. As before any ablation, a pregnancy test will be done the day before or the day of the procedure
  • Patient less than 18 years old
  • Patient under guardianship
  • Patient deprived of their liberty by a court decision

Key Trial Info

Start Date :

June 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2018

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT01521988

Start Date

June 1 2012

End Date

April 1 2018

Last Update

May 29 2018

Active Locations (15)

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Page 1 of 4 (15 locations)

1

CHU de Brest

Brest, France

2

CHU Grenoble

Grenoble, France, 38000

3

CH La Rochelle

La Rochelle, France

4

AP-HM - Hôpital Nord

Marseille, France