Status:

COMPLETED

Spinal Muscular Atrophy and Cardiac Autonomic Function

Lead Sponsor:

Centro Universitário Augusto Motta

Conditions:

Spinal Muscular Atrophy

Eligibility:

All Genders

5-25 years

Phase:

NA

Brief Summary

Respiratory dysfunction is the major cause of morbidity and mortality in patients with spinal muscular atrophy (SMA). Air stacking is a clearance airway technique frequently used but its effects on ca...

Detailed Description

Background: Respiratory dysfunction is the major cause of morbidity and mortality in patients with spinal muscular atrophy. Air stacking is a clearance airway technique frequently used but its effects...

Eligibility Criteria

Inclusion

  • diagnosis of SMA types II and III,
  • absence of acute respiratory disease in the last two weeks,
  • agreement to participate in the study,
  • according written informed consent and
  • at least 5 years old.

Exclusion

  • respiratory disease in the last two weeks

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2011

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT01522079

Start Date

January 1 2011

End Date

October 1 2011

Last Update

January 31 2012

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