Status:
COMPLETED
A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
Lead Sponsor:
Emory University
Collaborating Sponsors:
University of California, Los Angeles
Oregon Health and Science University
Conditions:
Temporomandibular Joint Dysfunction
Pain
Eligibility:
All Genders
18-90 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether the administration of hyaluronic acid or corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain relief and impro...
Detailed Description
This study will enroll patients with temporomandibular joint dysfunction who are deemed appropriate candidates for irrigation of their jaw joints secondary to pain or limited opening. At the completio...
Eligibility Criteria
Inclusion
- age greater than 18 years
- arthralgia of one or both temporomandibular joints
- Wilkes II to IV internal derangement of the symptomatic joint OR
- limited opening of \<35 mm
Exclusion
- myofascial pain as the primary source of pain
- cervical pain as the primary source of pain
- systemic arthropathy
- fibromyalgia
- use of NSAIDS within 48 hours
- allergy to study medications
- edentulous subjects
- pregnancy or breast feeding
- current physical therapy, muscle relaxants or antiseizure medications
- current use of a splint issued within last 12 weeks
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2016
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT01524913
Start Date
January 1 2012
End Date
April 1 2016
Last Update
May 5 2017
Active Locations (5)
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1
University California Los Angeles
Los Angeles, California, United States, 90024
2
Emory University
Atlanta, Georgia, United States, 30322
3
University of Cinncinati
Cinncinati, Ohio, United States, 45219
4
Oregon Health Sciences University
Portland, Oregon, United States, 97239