Status:

COMPLETED

Safety, Tolerability, and Immunogenicity of Zoster Vaccine Live (ZOSTAVAX™) in Healthy Adults in India (V211-025)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Herpes Zoster

Shingles

Eligibility:

All Genders

50+ years

Phase:

PHASE3

Brief Summary

This study will determine if ZOSTAVAX™ is safe, tolerable, and immunogenic in healthy adults in India.

Eligibility Criteria

Inclusion

  • No fever on day of vaccination
  • Females have a negative pregnancy test and use an acceptable method of birth control, or are postmenopausal
  • Underlying chronic illnesses must be stable

Exclusion

  • History of hypersensitivity reaction to any vaccine component
  • Prior receipt of a varicella or zoster vaccine
  • Prior history of herpes zoster
  • Have recently had another vaccination
  • Have recently received blood products other than autologous blood transfusion
  • Pregnant or breast feeding
  • Use of immunosuppressive therapy
  • Known or suspected immune dysfunction
  • Use of nontopical antiviral therapy with activity against herpesvirus

Key Trial Info

Start Date :

October 31 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 9 2013

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT01527370

Start Date

October 31 2012

End Date

April 9 2013

Last Update

September 18 2018

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Safety, Tolerability, and Immunogenicity of Zoster Vaccine Live (ZOSTAVAX™) in Healthy Adults in India (V211-025) | DecenTrialz