Status:
COMPLETED
MicroRNA Diagnostics in Subarachnoid Hemorrhage
Lead Sponsor:
Rigshospitalet, Denmark
Collaborating Sponsors:
Bispebjerg Hospital
Conditions:
Subarachnoid Hemorrhage
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to compare the profile of microRNA in cerebrospinal fluid from patients suffering subarachnoid hemorrhage with and without delayed cerebral ischemia.
Detailed Description
In this study of patients suffering an aneurysmal subarachnoid hemorrhage (SAH) we would like to investigate the pathophysiological mechanisms that lead to the phenomenon delayed cerebral ischemia (DC...
Eligibility Criteria
Inclusion
- Patient admitted to the neurointensive care unit with aneurismal subarachnoid hemorrhage
- External ventricular drainage with 5 days of ictus
- Age \> 18 years
Exclusion
- Glasgow Coma Score (GCS) continuously \< 7 during the first 5 days following ictus
- A known and proven complication (rebleeding, clip/coil complication, cardiopulmonal complication requiring full sedation, ventriculitis e.g.) leads to a GCS \< 7 thereby preventing the detection of DCI.
Key Trial Info
Start Date :
February 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01791257
Start Date
February 1 2013
End Date
January 1 2014
Last Update
April 8 2014
Active Locations (2)
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1
Rigshospitalet
Copenhagen, Denmark, 1302
2
Bispebjerg Hospital
Copenhagen, Denmark, 2400