Status:
UNKNOWN
The Histological Analysis in Renal Transplantation Patients With Deterioration of Graft Function
Lead Sponsor:
Shanghai Zhongshan Hospital
Conditions:
Chronic Allograft Dysfunction
Eligibility:
All Genders
18+ years
Brief Summary
Identify the cause of chronic allograft dysfunction using a combination of comprehensive clinical and histologic information in Chinese renal transplant recipients, then to identify the position of CN...
Eligibility Criteria
Inclusion
- 18 years of age or older
- Kidney transplant recipients, only including recipients of living-donor grafts
- Underwent an allograft biopsy between January 2005 and December 2011 because of developing deterioration of graft function\*.
- Deterioration of function was defined as (1) an unexplained and persistent greater than or equal to 25% increase of CR over baseline (in the absence of potential confounding factors) or (2) new onset proteinuria (defined as albumin/CR ratio ≥0.2 or a protein/CR ratio \>0.5).
Exclusion
- Multiple organ transplants, prior transplant with any other organ or tissue
- Patients who did not have the information regarding the pathological diagnosis
- Patients who did not have the histological sections of the allograft biopsy
Key Trial Info
Start Date :
May 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2013
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01794871
Start Date
May 1 2012
End Date
August 1 2013
Last Update
February 22 2013
Active Locations (1)
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1
Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, China, 200032