Status:

UNKNOWN

Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery

Lead Sponsor:

Johann Wolfgang Goethe University Hospital

Conditions:

Primary Malignant Neoplasm of Nervous System

Glioma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The investigators hypothesize that the rate of radiologically complete resections of contrast-enhancing brain tumors following surgeries aided by use of 5-ALA induced fluorescence guidance and use of ...

Eligibility Criteria

Inclusion

  • adult patient (\> 18 years) able to give informed consent
  • primary supratentorial intra-axial brain tumor exhibiting contrast enhancement suspected to be malignant glioma
  • tumor must be deemed completely resectable by neurosurgeon
  • diagnostic MRI

Exclusion

  • patient unable or unwilling to give informed consent
  • infratentorial tumor location
  • tumor location in or near eloquent areas
  • multifocal tumor
  • existance of contraindications to undergo MRI examination
  • previous surgical treatment for an intraaxial brain tumor

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2016

Estimated Enrollment :

108 Patients enrolled

Trial Details

Trial ID

NCT01798771

Start Date

March 1 2013

End Date

February 1 2016

Last Update

February 26 2013

Active Locations (1)

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Klinik für Neurochirurgie Johann Wolfgang Goethe University

Frankfurt am Main, Hesse, Germany, 60528