Status:
COMPLETED
Norepinephrine Transporter Availability in PTSD
Lead Sponsor:
Emory University
Conditions:
Posttraumatic Stress Disorder
Eligibility:
MALE
30-70 years
Phase:
PHASE1
Brief Summary
The objective of this proposal is to collect pilot data to characterize the binding of \[11C\]MENET in combat-exposed war veterans with posttraumatic stress disorder (PTSD). Approximately two hundred ...
Eligibility Criteria
Inclusion
- PTSD as determined by the Structural Clinical Interview for DSMIV (SCID) interview of PTSD and the Clinical Administered PTSD Scale (CAPS).
- Veteran with history of active duty service and currently discharged from active duty service
- Free of psychotropic medication for four weeks before the study
Exclusion
- History of shrapnel or other foreign bodies which would preclude MRI scanning
- Meningitis
- Traumatic brain injury
- Neurological disorder or organic mental disorder
- History of loss of consciousness
- Current or lifetime history of alcohol abuse or substance abuse or dependence base on the SCID
- Current or lifetime history of schizophrenia, schizoaffective disorder, or bulimia based on the SCID
- History of serious medical or neurological illness, such as cardiovascular, gastrointestinal, hepatic, renal, neurologic or other systemic illness
- Evidence of a major or neurological illness on physical examination or as a result of laboratory studies
- positive urine toxicology screen
- Current steroid use
Key Trial Info
Start Date :
June 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2013
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT01799837
Start Date
June 1 2012
End Date
July 1 2013
Last Update
September 11 2013
Active Locations (1)
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1
Emory University
Atlanta, Georgia, United States, 30329