Status:
COMPLETED
Urinary NGF as A Biomarker for Acute Bacterial Cystitis
Lead Sponsor:
Buddhist Tzu Chi General Hospital
Conditions:
Urinary Tract Infection
Eligibility:
FEMALE
20-90 years
Phase:
NA
Brief Summary
This study will enroll 30 female patients with the first time urinary tract infection (UTI), 30 female patients with recurrent UTI and 10 female without any prior history of UTI or urinary tract patho...
Detailed Description
Recurrent UTI is a very bothersome and a popular problem in the urogynecology clinical practice. According to the International Urogynecological Association (IUGA)/International Continence Society (IC...
Eligibility Criteria
Inclusion
- Female adults aged ≥ 20 years.
- All patients should be proven to have UTI by detecting pyuria in urinalysis (WBC\>10 per high power field) and had a positive urine culture result.
- A KUB film, and renal sonography will be performed to exclude to possibility of urolithiasis or other urinary tract pathology.
- Not yet have lower urinary tract surgery in the past.
- The patient has not yet accepted anticholinergic medication
- Patient or his legally acceptable representative has signed the written informed consent form.
Exclusion
- Patients with severe cardiopulmonary disease and such as congestive heart failure, arrhythmia, poorly controlled hypertension, not able to receive regular follow-up.
- Patients with uncontrolled confirmed diagnosis of acute urinary tract infection.
- Patients have laboratory abnormalities at screening including: (1) Aspartate aminotransferase (AST) \> 3 x upper limit of normal range. (2) Alanine aminotransferase (ALT) \> 3 x upper limit of normal range. (3) Patients have abnormal serum creatinine level \> 2 x upper limit of normal range.
- Female patients who is pregnant, lactating, or with child-bearing potential without contraception.
- Patients with any other serious disease or condition considered by the investigator not suitable for entry into the trial.
- Patients participated investigational drug trial within 1 month before entering this study.
- Patient or his legally written informed consent hadn't been obtained.
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT01800799
Start Date
February 1 2013
End Date
December 1 2014
Last Update
February 17 2017
Active Locations (1)
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1
Buddhist Tzu Chi General Hospital
Hualien City, Taiwan, 970