Status:
COMPLETED
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Sepsis
SIRS(Systemic Inflammatory Response Syndrome)
Eligibility:
All Genders
18+ years
Brief Summary
The imbalance between anti- and pro-inflammation often occurs in patients with sepsis. And continuous such imbalance could lead to immunoparalysis, which is characterized by loss of delayed type hyper...
Eligibility Criteria
Inclusion
- age over 18 years old;
- Fulfilled at least two criteria of systemic inflammatory response syndrome (a) core temperature higher than 38 ℃ or lower than 36 ℃ (b)respiratory rate above 20/min, or carbon dioxide partial pressure below 32 mmHg (c) pulse rate above 90/min, and (d) white blood cell count greater than 12,000/μl or lower than \< 4,000/μl or less than 10% of bands.
- Clinically suspected infection;
Exclusion
- were under 18 years of age;
- were refused by the patients or his/her familiality;
- were suffering from acquired immunodeficiency syndrome,viral hepatitis,autoimmune diseases and hematology;
- use medicine which can affect immune system,such as Glucocorticoid and Immunosuppressant
- died within 24h after being taken into the ICU, or refused to get involved in the study, or gave up treatment during the period of observation
Key Trial Info
Start Date :
August 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT01801839
Start Date
August 1 2012
Last Update
January 28 2016
Active Locations (1)
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1
Chinese PLA General Hospital
Beijing, China