Status:
TERMINATED
Walking Interventions, Cognitive Remediation and Mild Cognitive Impairment
Lead Sponsor:
Pennington Biomedical Research Center
Conditions:
Cognitive Impairment
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effects of a coordinated intervention of cognitive remediation training (CRT) and walking intervention on cognition and gait in the elderly.
Detailed Description
This is a single blind randomized study designed to understand the effects of different interventions, walking interventions and cognitive remediation in particular, towards cognition and gait in the ...
Eligibility Criteria
Inclusion
- Men and women meeting all criteria listed below will be included in the study:
- Subjects between 65-85 years of age inclusive
- Subjects with Short Physical Performance Battery of 10 or greater
- Subjects averaging less than 5,000 steps per day
- Subjects with Mini Mental State Exam 25-28, inclusive
- Subjects with normal for age physical-neurological exam
- Subjects able to walk a city block without a walking aid
- Written Informed Consent obtained PRIOR to performing any study procedures
Exclusion
- Subjects with difficult walking due to pain or posture
- Subjects with difficulty in using computer due to significant visual and/or fine motor impairment
- Subjects with large weight loss (\>15 Kilogram) in the last 12 months
- Subjects with geriatric depression scale \> 9.
- Subjects with Malignancies in the past 5 years, with the exception of skin cancer therapeutically controlled
- Subjects with abnormal electrocardiogram results. These include: a resting heart rate below 40 bpm or above 100 bpm, previously unknown and/or untreated atrial fibrillation or flutter, evidence of a third degree A-V block, a previously undocumented left bundle branch block, S-T segment depression of greater than 2 mm, evidence of a previous MI, or any other findings that in the clinical judgment of the medical investigator preclude participation in an exercise intervention.
- Subjects with shortness of breath, exertional angina, uncontrolled high blood pressure or any other chronic medical condition deemed by the physician to preclude participation in an exercise intervention.
- Subjects with any other medical condition or disease that is life-threatening or that can interfere with, or be aggravated by, exercise.
- Subjects who currently smoke.
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
End Date :
November 1 2014
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01801943
Start Date
February 1 2013
End Date
November 1 2014
Last Update
September 23 2022
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808