Status:

COMPLETED

An Adaptive Treatment Strategy for Adolescent Depression

Lead Sponsor:

University of Minnesota

Conditions:

Adolescent Depression

Eligibility:

All Genders

12-17 years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of the study is: 1. to find out how long teenagers getting talk therapy (interpersonal psychotherapy) for depression should get therapy before the therapist decides whether or not the tee...

Detailed Description

Study Procedures This study has three phases: 1. The screening and eligibility phase: Parent and child will conduct an initial evaluation that will last about 4 hours. The evaluator will ask que...

Eligibility Criteria

Inclusion

  • Adolescent meets DSM-IV-TR criteria for a diagnosis of Major Depressive Disorder, Dysthymia, or Depressive Disorder NOS; demonstrate symptoms of depression (CDRS-R \> 35); and demonstrate impairment in general functioning (CGAS \< 65).
  • Adolescents and parents must be English-speaking

Exclusion

  • Adolescent meets criteria for a diagnosis of Schizophrenia, Bipolar Disorder, Psychosis, Substance Abuse, OCD, Conduct Disorder, Eating Disorder, PDD, or intellectual disability disorder.
  • Depressed adolescents who are actively suicidal with a plan and/or intent
  • Adolescent that are already receiving treatment for depression or if they are taking medication for a psychiatric diagnosis other than ADHD. Depressed adolescents with a comorbid diagnosis of ADHD who are on a stable dose of stimulant medication (\> 3 months) will be eligible to participate in the studies.
  • Adolescent that have already received an adequate trial of IPT-A or fluoxetine.
  • Female adolescents who are pregnant, breastfeeding, or having unprotected sexual intercourse.

Key Trial Info

Start Date :

November 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01802437

Start Date

November 1 2010

End Date

June 1 2016

Last Update

July 11 2019

Active Locations (1)

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1

University of Minnesota, Department of Psychiatry

Minneapolis, Minnesota, United States, 55454