Status:
COMPLETED
Magnesium Sulphate and Rocuronium in Patients Over 60
Lead Sponsor:
Pedro Rotava
Collaborating Sponsors:
Instituto Nacional de Cancer, Brazil
Conditions:
Head and Neck Cancer
Eligibility:
All Genders
60+ years
Phase:
PHASE1
Brief Summary
The purpose of this study is to evaluate the effects of MgSO4 administration on the pharmacodynamics of rocuronium in patients with 60 or more years of age.
Eligibility Criteria
Inclusion
- 60 years or older
- ASA physical status I-III
- Scheduled for elective oncologic head and neck surgery
Exclusion
- Severe renal insufficiency (calculated creatinine clearance \< 30 ml/min)
- Pre-operatory serum magnesium values \> 2.5 mEq/l
- Patients receiving medications known to affect neuromuscular function (furosemide, aminoglycoside, anticonvulsivants, calcio channel blocker, litium, azatioprine, cyclofosfamide)
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT01804205
Start Date
September 1 2008
End Date
March 1 2012
Last Update
March 14 2018
Active Locations (1)
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1
Instituto Nacional de Câncer
Rio de Janeiro, Brazil, 20230130