Status:
COMPLETED
Non-invasive Measurement of Microvascular Blood Flow During Mild External Compression of the Leg
Lead Sponsor:
University of California, San Diego
Conditions:
Diabetes
Healthy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
SPECIFIC AIMS The limbs of diabetic patients are associated with decreases in capillary density, arterial inflow, and local blood flow of the leg. Decreased perfusion adversely affects wound healing ...
Detailed Description
BACKGROUND AND SIGNIFICANCE Therapies utilizing external compression of the leg prevent deep venous thrombosis, decrease lower extremity edema, manage chronic venous insufficiency, and increase heali...
Eligibility Criteria
Inclusion
- As long as there is no exclusion criteria
Exclusion
- History of lower extremity vascular diseases such as atherosclerosis, intermittent claudication, acute or chronic deep venous thrombosis, presence of ankle edema, stasis dermatitis, active lower extremity ulcers or wounds, diabetic foot ulcers, diabetic neuropathy, history of lower extremity surgery.
- Pregnant women.
- Patients with abnormally large or misshapen legs.
- Patients with existing ulcers.
- Patients with poor underlying health.
- Patients with allergies to the study materials.
- Patients who recently developed deep venous thrombosis (6 months)
- Patients with congenital A/V malformations.
- Patients with paraplegia.
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01804478
Start Date
May 1 2005
End Date
February 1 2013
Last Update
March 5 2013
Active Locations (1)
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1
University of California San Diego
San Diego, California, United States, 92103