Status:
COMPLETED
Investigating Inter-individual Variability in Glycemic and Insulin Responses
Lead Sponsor:
Institute for Human Development and Potential (IHDP), Singapore
Conditions:
Hyperglycemia
Insulin Sensitivity
Eligibility:
MALE
21-40 years
Phase:
NA
Brief Summary
This study aims to test the following hypothesis in healthy lean young men: * There are differences in glycemic response (GR) and insulin response (IR) between Chinese, Malay and Asian-Indian * There...
Detailed Description
There is extensive evidence that numerous biological digestive factors varies between individuals and influence postprandial glycemic response (GR) and insulin response (IR), which are well establishe...
Eligibility Criteria
Inclusion
- Be willing and able to comply with study procedures and given written informed consent
- Chinese/Malay/Indian males, aged 21-40 years old
- Body mass index (BMI) between 18.5 - 24.9 kg/m2
- Fasting blood glucose between 4 - 6 mmol/L
- Sedentary adults, with \<1 episode of exercise per week
- Not have a history of food allergies or food intolerances
- Be a non-smoker
- Drinks less than 3 units of alcohol per day
- Not taking antibiotics for the past 3 weeks
Exclusion
- Subjects with known chronic diseases, including diabetes, untreated hypertension, renal impairment, gastrointestinal problems, and other significant medical conditions
- BMI \<18.5 kg/m2 or \>25 kg/m2
- Fasting blood glucose ≥7.0mmol/l
- Alcohol consumption \>3 drinks / day
- Use of medications known to affect glucose metabolism
- Recent changes in weight of \>5% over the past 3 months
- Significant changes in diet over the past 3 months
- History of eating disorders or irregular eating habits
- Taking antibiotics medications over the past 3 weeks
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT01804738
Start Date
March 1 2013
End Date
June 1 2014
Last Update
March 14 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Clinical Nutrition Research Centre
Singapore, Singapore, 117599