Status:
COMPLETED
Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients
Lead Sponsor:
University Hospital, Bordeaux
Collaborating Sponsors:
Teleflex
Conditions:
Ventilator Acquired Pneumonia
Aspiration
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the impact of an optimized suctioning procedure on the risk of endotracheal microaspiration, measured by tracheal to oropharyngeal ratio of amylase enzymatic a...
Detailed Description
• Study design : This is an open prospective, cross-over cohort study, including patients ventilated in one medical intensive care unit. Two procedures will be compared in two distinct, randomly decid...
Eligibility Criteria
Inclusion
- Intubated with a subglottic secretion drainage device
- ventilated more than 48 hours
- patients yielding a significant tracheal suctioning volume (on a semi-qualitative evaluation: ≥ ++ on a scale consisting of 0,+,++,+++)
Exclusion
- paralysed patients
- patients with Ramsay 1, 2
- patients breathing spontaneously
- patients less than 18 years old
- patients in a moribund state
- contra-indication for suctioning procedure (risk of haemorrhage, bronchospasm, Acute Respiratory Distress Syndrome with P/F \< 100, malformation or tracheal fistula)
- bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease
- patients necessitating a closed-suctioning device (prevention of respiratory multiresistant bacteria transmission, Acute Respiratory Distress Syndrome with P/F ratio \< 100)
- pregnant women
Key Trial Info
Start Date :
November 12 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 4 2016
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT01807884
Start Date
November 12 2014
End Date
March 4 2016
Last Update
July 13 2017
Active Locations (1)
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1
Hospital Pellegrin
Bordeaux, Gironde, France, 33000