Status:
COMPLETED
Comparison of Two Different Membranes
Lead Sponsor:
Tufts University
Conditions:
Partial Edentulism
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the study is to compare one material called "Mucograft" with another material called "Dynamatrix." These materials are used as a type of a barrier (made from pig material also known as ...
Detailed Description
A) Aim/Hypothesis/Objective The objective of this study is to compare two different membranes, Mucograft and Dynamatrix, clinically, radiographically, and histologically when used for the ridge preser...
Eligibility Criteria
Inclusion
- Be at least 18 years of age.
- Have unsalvageable non-adjacent non-molar teeth: maxillary incisors, canines, and premolars, and mandibular canines and premolars that require an extraction with bone augmentation planned for delayed implant placement. If a subject has multiple teeth to be extracted, only one tooth will be included in the study.
- Patients who are currently treatment planned in the Tufts University School of Dental Medicine (TUSDM) periodontology clinic to receive bone augmentation and delayed implant placement and meet all medical and dental requirements of the TUSDM periodontology clinic for periodontal surgery (e.g., subjects with no diseases or medication allergies contraindicating periodontal surgery).
- Display no evidence of acute periodontal infection: e.g., abscess, suppuration, severe swelling and/or spontaneous bleeding.
- Smoke less than 10 cigarettes per day.
- Not participating in any other dental research study for the duration of this study.
Exclusion
- Have any known disease that interferes with periodontal surgery and would not allow the patient to be treatment planned for the procedures in the TUSDM periodontology clinic (e.g., severe anemia, low white blood cell count, bleeding or coagulation disorder, uncontrolled hypertension, recent myocardial infarction (within 6 months of enrollment), poorly controlled diabetes, HIV/AIDS (self-reported), history of or currently undergoing head and neck radiation, history of or currently taking bisphosphonates).
- Have a history of severe psychological conditions or limited mental capacity.
- Be a pregnant or lactating female (self-reported) (following TUSDM periodontology clinic guidelines elective surgical procedures and radiographs/CBCT scans are usually postponed until after delivery).
- Individuals opposed to having porcine derived materials placed in their mouth.
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT01808794
Start Date
January 1 2013
End Date
January 1 2016
Last Update
February 19 2020
Active Locations (1)
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1
Tufts University School of Dental Medicine
Boston, Massachusetts, United States, 02111