Status:

COMPLETED

Brexpiprazole in Patients With Schizophrenia

Lead Sponsor:

H. Lundbeck A/S

Collaborating Sponsors:

Otsuka Pharmaceutical Co., Ltd.

Conditions:

Schizophrenia

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

To determine the safety and efficacy of brexpiprazole during long-term treatment.

Eligibility Criteria

Inclusion

  • The patient has completed the lead-in study 14644A.
  • The patient is judged to potentially benefit from 52-week treatment with brexpiprazole according to the clinical opinion of the investigator.
  • The patient agrees to protocol-defined use of effective contraception.

Exclusion

  • The patient has been diagnosed with a primary psychiatric disorder other than schizophrenia during Study 14644A.
  • The patient has a clinically significant unstable illness diagnosed during Study 14644A.
  • The patient, in the opinion of the investigator or according to Columbia-Suicide Severity Rating Scale (C-SSRS), is at significant risk of suicide.
  • The patient has an abnormal ECG or other abnormal ECG tests that are, in the investigator's opinion, clinically significant.
  • The patient is, in the investigator's opinion, unlikely to comply with the protocol or is unsuitable for any reason.
  • Other inclusion and exclusion criteria may apply.

Key Trial Info

Start Date :

July 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2015

Estimated Enrollment :

210 Patients enrolled

Trial Details

Trial ID

NCT01810783

Start Date

July 1 2013

End Date

December 1 2015

Last Update

March 27 2017

Active Locations (48)

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Page 1 of 12 (48 locations)

1

US010

Anaheim, California, United States

2

US020

Cerritos, California, United States

3

US009

Escondido, California, United States

4

US022

Garden Grove, California, United States

Brexpiprazole in Patients With Schizophrenia | DecenTrialz