Status:
COMPLETED
Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery
Lead Sponsor:
University Hospital, Clermont-Ferrand
Conditions:
Patients Undergoing a Lumbar Slipped Disc Surgery
Eligibility:
All Genders
18-85 years
Phase:
PHASE3
Brief Summary
The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, ...
Detailed Description
Visit 1 (J-30 J-1): pre-inclusion visit During a follow-up visit usual pathology, the doctor will propose to the patient to participate in the protocol. Information Form will be given to the patient t...
Eligibility Criteria
Inclusion
- Patients undergoing a lumbar slipped disc surgery
- Aged 18 to 85 years.
- ASA score I-III
- Having given their consent.
- Affiliated with a social security scheme
Exclusion
- Patients who must be operated urgently.
- Patients previously operated for lumbar spinal surgery.
- Expected duration of surgery more than 3 hours.
- Severe renal impairment defined by a creatinine clearance less than or equal to 30 mL/min.
- Taking long-term strong opiates .
- Taking long-term corticosteroids or within 48 hours before surgery.
- Taking pregabalin or gabapentin within 48 hours before surgery.
- Drug addiction.
- Patients with cognitive impairment (judged by the investigator) that may interfere with:
- informed consent, the collection of endpoints, the use of auto-controlled analgesia.
- Pregnant or nursing women.
- Refusal of the protocol.
- Minor or major protected patients.
- Allergy or other cons-indication to the molecules used in the protocol.
Key Trial Info
Start Date :
December 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 10 2017
Estimated Enrollment :
162 Patients enrolled
Trial Details
Trial ID
NCT01811251
Start Date
December 1 2012
End Date
October 10 2017
Last Update
May 28 2019
Active Locations (1)
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1
CHU Clermont-Ferrand
Clermont-Ferrand, France, 63003