Status:
COMPLETED
Interleukin-1 Receptor Antagonist Gene Polymorphism and Adverse Pregnancy Outcome in Turkish Women
Lead Sponsor:
Selcuk University
Conditions:
Periodontitis
Eligibility:
FEMALE
18-35 years
Brief Summary
The investigators hypothesized that the IL-1A (+4895), IL-1B (+3954), and IL-1RN gene polymorphisms may be associated with PLBW. Smoking has been well documented by numerous studies as a major environ...
Detailed Description
Pregnant women between 18-35 years of age with single gestation and with ≥20 on-crowded teeth excluding third molars were included in this study. Subjects were divided into normal birth (NB) and PLBW ...
Eligibility Criteria
Inclusion
- Subjects were divided into normal birth (NB) and PLBW groups on the basis of their pregnancy outcome. Women who delivered an infant with a birth weight of more than 2500 g after 37 weeks of gestation were placed in the NB group.
Exclusion
- Current/past tobacco user, alcohol abuse, history of high-risk gestation, hypertension, gestational diabetes, any systemic disease and placenta previa were the exclusion criteria for this study.
Key Trial Info
Start Date :
January 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2005
Estimated Enrollment :
156 Patients enrolled
Trial Details
Trial ID
NCT01812083
Start Date
January 1 2004
End Date
February 1 2005
Last Update
March 15 2013
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