Status:
TERMINATED
Mechanism and Treatment of Sympathetically Maintained Pain
Lead Sponsor:
The Cleveland Clinic
Collaborating Sponsors:
Murdoch University
Conditions:
Complex Regional Pain Syndrome (CRPS)
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
40 CRPS patients will be recruited over a three-year period (target of 160 patients at all sites). Assessment of exclusion criteria will be undertaken during initial recruitment. Exclusion criteria ar...
Detailed Description
Patients diagnosed with CRPS and control subjects will be enrolled in the study. The CRPS participants will be administered with phenylephrine (day 1) and clonidine (day 2). The control participants w...
Eligibility Criteria
Inclusion
- CRPS patients
Exclusion
- \<18 years
- a second chronic pain syndrome that would interfere with pain rating
- psychiatric comorbidity
- pain in both hands or feet
- pregnancy or breastfeeding
- sympathectomy in the affected limb
- use of topical medication
- known sensitivity to alpha 1- adrenoceptor agonists or other contraindications
Key Trial Info
Start Date :
August 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT01813149
Start Date
August 1 2012
End Date
December 1 2016
Last Update
January 13 2021
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195