Status:
COMPLETED
Effects of Intensive Aerobic and Muscle Endurance Exercise in Patients With Systemic Sclerosis - a Pilot Study
Lead Sponsor:
Karolinska University Hospital
Conditions:
Systemic Sclerosis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The hypothesis is that intensive aerobic and endurance muscle training is safe and beneficial in patients with systemic sclerosis and concurrent interstitial lung disease. The purpose of the study is...
Detailed Description
The purpose of the study is to examine the effect of an eight week intensive aerobic exercise and muscle endurance training program for patients with systemic sclerosis and 50-100 % of forced vital ca...
Eligibility Criteria
Inclusion
- limited or diffuse SSc
- age 18-80 years
- diagnosis duration \> 1 year
- unchanged medication since 3 months
- 50-100 % of normal vital capacity
- exercising \< once a week
- speak and understand the Swedish language
- average or below aerobic capacity according to the submaximal treadmill test (\< 27 ml/kg x min for women and \< 30 ml/kg x min for men)
- \< 20 % reduced muscle endurance according to the Functional Index-2
Exclusion
- Sendoxan treatment for alveolitis
- Pulmonal hypertension (PAH)
- heart condition contraindicating exercise
- \< 50 % of normal vital capacity
- reduced kidney function
- not being able to perform the exercise program
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2010
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT01813578
Start Date
October 1 2009
End Date
April 1 2010
Last Update
March 19 2013
Active Locations (1)
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1
Karolinska Univeristy Hospital, Solna
Stockholm, Stockholm County, Sweden, 171 76