Status:

COMPLETED

Immunogenicity and Safety of Trivalent Influenza Vaccine in Pregnant and Nonpregnant HIV Uninfected Women

Lead Sponsor:

University of Witwatersrand, South Africa

Collaborating Sponsors:

Bill and Melinda Gates Foundation

Conditions:

Influenza

Eligibility:

FEMALE

18-39 years

Phase:

PHASE4

Brief Summary

The overall aim of this project is to evaluate the immunogenicity of TIV vaccination in HIV-uninfected pregnant women compared with HIV-uninfected non-pregnant women in 2013. Safety data will also be ...

Eligibility Criteria

Inclusion

  • All women
  • (i) Documented to be HIV-1 uninfected on one assay used in the Prevention of Mother to Child Transmission (PMTCT)/ other program undertaken within 12 weeks of study enrolment.
  • (ii) Able to understand and comply with planned study procedures. (iii) Provides written informed consent prior to initiation of study. (iv) Women age ≥ 18 years to \< 39 years.
  • pregnant women
  • (i) Gestational age ≥20 weeks to \<36 weeks documented by the approximate date of the last menstrual period and corroborated by physical exam and sonar report if available.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2013

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    April 1 2014

    Estimated Enrollment :

    150 Patients enrolled

    Trial Details

    Trial ID

    NCT01816464

    Start Date

    September 1 2013

    End Date

    April 1 2014

    Last Update

    January 12 2015

    Active Locations (1)

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    Nrf/Dst Vpd Rmpru

    Soweto, GP, South Africa, 2055