Status:

TERMINATED

Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles

Lead Sponsor:

Andros Day Surgery Clinic

Conditions:

In Vitro Fertilization

Ovarian Stimulation

Eligibility:

FEMALE

18-40 years

Phase:

PHASE4

Brief Summary

This randomized controlled trial has been designed for carrying out a comparison of new AMH (Anti-Müllerian Hormone)-based individualized treatment (using a nomogram) with the wide accepted age-based ...

Detailed Description

Before clinicians can adopt any model into routine clinical practice, the accuracy of the model should be independently evaluated in a population different from the one on which the model was elaborat...

Eligibility Criteria

Inclusion

  • first or second IVF/ICSI attempt (the second one after 6 months from the first one);regular menstrual cycles (25-33 days);female age ≤ 40; day 3 FSH ≤ 15IU/L;treatment with a long GnRH agonist protocol (buserelin)+rFSH;BMI: \>18 and ≤ 25 kg/m2;presence of both ovaries.

Exclusion

  • irregular cycles, anovulatory infertility, endometriosis III-IV stage AFS, use of adjunctive therapies for stimulation, evidence of PCO status, previous ovarian surgery, presence of ovarian cysts, history of PID, use of hormonal contraception in the previous 3 months, any known metabolic or endocrinological disease, AMH levels \< 1 and \> 4.0 ng/ml

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2016

Estimated Enrollment :

194 Patients enrolled

Trial Details

Trial ID

NCT01816789

Start Date

March 1 2013

End Date

July 1 2016

Last Update

December 23 2016

Active Locations (1)

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ANDROS Day Surgery Clinic

Palermo, Sicily, Italy, 90144