Status:
COMPLETED
Sub-thalamic Nucleus Stimulation in Parkinson Disease
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Parkinson's Disease
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. This procedure performed in two steps using electrophysiology. This study is a prospectiv...
Detailed Description
Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. This procedure performed in two steps using electrophysiology (Limousin et al., 1995) to ...
Eligibility Criteria
Inclusion
- Age : between 18 and 70 years old
- Parkinson disease in fluctuation state despite the use of an optimal medical treatment
- Dopa sensibility higher than 50% with the L-DOPA test
- Normal MRI
- Mattis Scale \> 130
- Surgical indication approved by a multidisciplinary team
- Patient covered by a social insurance
- Informed consent signed by patient and investigator
Exclusion
- Patients with surgical or anesthetic contraindications
- Cerebral atrophy or signal abnormalities on MRI
- Severe Depressive State : The Beck Scale score \> 15
- Women of childbearing potential without efficient contraceptive mean
- Need of long-term antithrombotic treatment
Key Trial Info
Start Date :
March 11 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 9 2016
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01817088
Start Date
March 11 2013
End Date
September 9 2016
Last Update
August 24 2017
Active Locations (1)
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1
University Hospital
Bordeaux, France, 33076