Status:

UNKNOWN

Safety and Efficacy of Oral Versus Intravenous Amiodarone in the Treatment of AF

Lead Sponsor:

Western Galilee Hospital-Nahariya

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Atrial fibrillation (AF) remains a significant contributor to cardiovascular morbidity. Amiodarone is a potent antiarrhythmic drug; however, patients receiving IV amiodarone are at high risk for phleb...

Detailed Description

Atrial fibrillation (AF) is the most common heart rhythm abnormality worldwide. Three therapeutic goals should be considered for each patient: Rate control, maintenance of sinus rhythm and prevention ...

Eligibility Criteria

Inclusion

  • Over 18 years of age,
  • Patients who will be admitted to the ICCU / ICU wards
  • Patients with recent onset of atrial fibrillation (duration \< 48h).

Exclusion

  • Age \< 18 years
  • Baseline systolic blood pressure \< 100 mm/hg
  • Known thyroid disease
  • Serum potassium \< 3.5 mmol/l
  • Pretreatment with amiodarone
  • Pregnant or lactating women.
  • Participation in other clinical trial.

Key Trial Info

Start Date :

May 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2015

Estimated Enrollment :

104 Patients enrolled

Trial Details

Trial ID

NCT01817439

Start Date

May 1 2013

End Date

May 1 2015

Last Update

March 25 2013

Active Locations (1)

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1

Western Galilee Hospital

Nahariya, Israel, Israel, 972