Status:
UNKNOWN
Amino Acids Expression Profiling of Patients With Sepsis
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Sepsis
Amino Acids
Eligibility:
All Genders
18+ years
Brief Summary
The patients with sepsis are in the state of hypermetabolism, increased resting energy expenditure, protein and fat catabolism disorder, negative nitrogen balance, insulin resistance, hyperglycemia, a...
Eligibility Criteria
Inclusion
- Male and female aged 18 years old and over;
- Clinically confirmed infection;
- Fulfilled at least two criteria of systemic inflammatory response syndrome (a) core temperature higher than 38 °C or lower than 36 °C (b)respiratory rate above 20/min, or PCO2 below 32 mmHg (c) pulse rate above 90/min, and (d) white blood cell count greater than 12,000/μl or lower than \< 4,000/μl or less than 10% of bands.
Exclusion
- parenteral nutrition;
- diabetes and other metabolic-related diseases;
- chronic liver disease;
- neutropenia (≤ 500 neutrophils/mm3);
- HIV infection;
- patients or their relatives refused.
Key Trial Info
Start Date :
March 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01818830
Start Date
March 1 2012
Last Update
March 27 2013
Active Locations (1)
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1
Chinese PLA General Hospital
Beijing, Beijing Municipality, China, 100853