Status:
UNKNOWN
Revascularization Strategies for STEMI; The CMR Endpoint Study
Lead Sponsor:
Unity Health Toronto
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Revascularization strategies for ST elevation myocardial infarction (STEMI) study (ASSIST-CMR) will compare the effects of two revascularization strategies \[same sitting multivessel primary PCI (SS-P...
Eligibility Criteria
Inclusion
- High risk ST elevation myocardial infarction evidenced by: ≥2 mm ST elevation in 2 anterior or lateral leads; or ≥2 mm ST elevation in 2 inferior coupled with ST depression in 2 contiguous anterior leads for a total ST deviation of ≥8 mm; or New left bundle branch block with at least 1 mm concordant ST elevation.
- Multivessel CAD as evidenced by ≥1 significant (≥70% by visual assessment or FFR\<0.80 for 50-70% stenosis) stenosis in non-IRA.
- Successful IRA-PCI with \<10% residual angiographic stenosis and TIMI III flow.
- Written informed consent.
Exclusion
- Age ≤ 18 years.
- Prior coronary artery bypass graft (CABG) surgery.
- Administration of thrombolytic therapy.
- Non-IRA stenosis is a chronic total occlusion or located in left main artery.
- Hemodynamic instability evidenced by BP\<90 mmHg, Killip class ≥2, need for inotropes/vasopressors.
- Known renal insufficiency (estimated GFR \< 50ml/min).
- Contraindication to CMR.
Key Trial Info
Start Date :
April 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2018
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT01818960
Start Date
April 1 2014
End Date
July 1 2018
Last Update
July 29 2016
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
London Health Sciences
London, Ontario, Canada, N6A 5A5
2
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8
3
Regina Qu'Appelle Health Region
Regina, Saskatchewan, Canada, S4P 0W5