Status:
COMPLETED
Pulse Pressure Variation for Prediction of Fluid Responsiveness in Coronary Artery Disease Patients With Diastolic Dysfunction
Lead Sponsor:
Yonsei University
Conditions:
Fluid Responsiveness Predictability
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
The investigators hypothesized that predictability of pulse pressure variation (PPV) on fluid responsiveness would be reduced in patients with coronary disease who have diastolic dysfunction.
Eligibility Criteria
Inclusion
- Patients older than 20 years
- scheduled for elective coronary artery bypass grafting
- normal diastolic function (E/E' \< 8) or diastolic dysfunction (E/E' \>15) according to preoperative Echocardiographic evaluation
Exclusion
- arrythmia,
- reduced left ventricular function (ejection fraction \< 40%)
- valvular heart disease requiring concomitant surgical correction
- pulmonary hypertension (mean pulmonary arterial pressure ≥30 mm Hg)
- peripheral arterial occlusive disease, pulmonary disease (asthma, chronic obstructive pulmonary disease, and lung resection)
- end-stage renal disease
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2013
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT01819571
Start Date
January 1 2012
End Date
October 1 2013
Last Update
February 19 2014
Active Locations (1)
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1
Department of anesthesiology and pain medicine
Seoul, Seoul, South Korea, 120-752