Status:
COMPLETED
L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
Lead Sponsor:
Taichung Veterans General Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
20-90 years
Phase:
PHASE2
PHASE3
Brief Summary
Cardiovascular disease (CVD) is the leading cause of Taiwan. L-carnitine (LC) and coenzyme Q10 is recognized as lipid soluble antioxidants. The purposes of this study are going to investigate the rela...
Eligibility Criteria
Inclusion
- Clinical diagnosis of coronary artery disease (CAD): CAD patients were identified as having at least 50% stenosis of one major coronary artery by cardiac catheterization or as have received percutaneous transluminal coronary angioplasty (PTCA).
- Health subjects: Subjects did not have any illnesses and a history of gastrointestinal disorder, cardiovascular disease (showed normal electrocardiogram), hypertension, hyperlipidemia, liver and renal disease, diabetes, cancer, alcoholism or other metabolic disease and exhibited normal blood biochemical values, including fasting blood glucose \< 6.11 mmol/L, blood urea nitrogen (BUN) \< 7.9 mmol/L, creatinine \< 123.8 umol/L, alkaline phosphates \< 190 U/L, glutamic oxaloacetic transaminase (GOT) \< 35 U/L and glutamic pyruvate transaminase (GPT) \< 45 U/L.
- Must be able to swallow tablets
Exclusion
- age \< 20 years old
- pregnancy women
- taking antioxidant vitamins supplements
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT01819701
Start Date
January 1 2013
End Date
February 1 2014
Last Update
March 13 2014
Active Locations (1)
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1
Taichung Verterans General Hospital
Taichung, Taiwan, 40705