Status:
COMPLETED
Brain Alterations and Cognitive Impairment in Older Adults With Heart Failure
Lead Sponsor:
University of Wisconsin, Madison
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Heart Failure
Eligibility:
All Genders
65-85 years
Brief Summary
Cognitive impairment, commonly reported as difficulty with memory and executive function, is a widely recognized clinical challenge for older persons with heart failure (HF). Little is known about the...
Detailed Description
Cognitive impairment, commonly reported as difficulty with memory and executive function, is a widely recognized clinical challenge for persons \> 65 years old with HF. Although the degree of cognitiv...
Eligibility Criteria
Inclusion
- 65 years old or older
- English speaking and writing;
- Stable guideline based medication regimen for at least four weeks prior to enrollment
- New York Heart Association classification I-IV
Exclusion
- Mini-Mental Status Exam score equal to or less than 24;
- Current diagnosis of neurological illnesses or movement disorders (e.g. Alzheimer's dementia, Parkinson's disease, Epilepsy);
- History of substance abuse/treatment;
- Untreated depression
- History of stroke;
- Hepatic insufficiency;
- Severe renal failure;
- Untreated anemia;
- Left ventricular assist device;
- History of the following within three months of study enrollment: acute myocardial infarction, unstable angina, coronary artery bypass surgery, percutaneous transluminal angioplasty, or biventricular pacemaker insertion;
- History of implantable device (or other MRI contraindications).
- Prisoners
- Pregnancy
Key Trial Info
Start Date :
April 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01821638
Start Date
April 1 2013
End Date
December 31 2018
Last Update
February 6 2019
Active Locations (1)
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1
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792