Status:
COMPLETED
Pain Control After Cardiac Surgery Using Intravenous Acetaminophen
Lead Sponsor:
The Cleveland Clinic
Conditions:
Pain
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Evaluate the efficacy of IV acetaminophen; compared to a placebo, in reducing opioid consumption and/or pain intensity scores after cardiac surgery.
Eligibility Criteria
Inclusion
- \- Males or females 18 years of age or older.
- Non-emergency cardiac surgery via a midline sternotomy at Cleveland Clinic Main Campus.
Exclusion
- Redo cardiac surgery.
- Combined CABG (Coronary Artery Bypass Graft)\& valve replacement, multiple valve replacements, Ascending aortic or aortic arch surgery.
- Weight \< 50 Kg or Body mass index \> 38 kg/m2.
- Left ventricle EF ¡Ü 35% ,Right ventricular moderate or severe dysfunction.
- Severe (3-4 +) Tricuspid Regurgitation.
- Recent stroke (within 6 months).
- Severe lung disease requiring home O2 therapy.
- Preoperative renal insufficiency (Creatinine \> 2.0) or on dialysis.
- History of liver cirrhosis or active liver disease.
- Chronic pain conditions controlled by preoperative opioid administration.
- Known allergy to acetaminophen or fentanyl.
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01822821
Start Date
March 1 2013
End Date
March 1 2015
Last Update
May 15 2017
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195