Status:
COMPLETED
Ketamine Versus Etomidate for Rapid Sequence Intubation
Lead Sponsor:
Hennepin Healthcare Research Institute
Conditions:
Airway Control
Anesthesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
Detailed Description
This study is a randomized controlled trial of etomidate versus ketamine during rapid sequence intubation (RSI). RSI refers to the process by which patients who require emergency airway management und...
Eligibility Criteria
Inclusion
- 18 years of age
- Undergoing rapid sequence intubation (RSI) in the Emergency Department
Exclusion
- Known contraindication to ketamine or etomidate
- Patient has a condition in which an increase in heart rate or blood pressure would be hazardous, as judged by the treating physician
- Patient is known or suspected of having increased intracranial pressure, based on the history and physical examination performed by the treating physician.
- Females of child-bearing age, defined as 18-50 years, who do not have a documented pregnancy test in this institution confirming that they are not pregnant or who do not have a confirmed surgical procedure preventing pregnancy, i.e., tubal ligation, hysterectomy. The timing of the pregnancy test at which the investigative team will consider a subject to be non-pregnant is a documented negative test during current hospitalization or upon direct transfer from outside institution during current illness.
- Patient declines participation in the trial by wearing a bracelet marked "KvE declined"
- Prisoner
Key Trial Info
Start Date :
September 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
143 Patients enrolled
Trial Details
Trial ID
NCT01823328
Start Date
September 1 2013
End Date
October 1 2015
Last Update
May 24 2019
Active Locations (1)
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1
Hennepin County Medical Center
Minneapolis, Minnesota, United States, 55415