Status:

COMPLETED

Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women

Lead Sponsor:

Rio de Janeiro State University

Collaborating Sponsors:

Laboratory for Clinical and Experimental Research on Vascular Biology

Conditions:

1- Microvascular Function

2-oxidative Stress

Eligibility:

FEMALE

19-50 years

Phase:

PHASE4

Brief Summary

The prevalence of obesity and type 2 diabetes mellitus (T2DM) has increased progressively in the past decades, and consequently, a higher incidence of cardiovascular diseases is observed. As this proc...

Eligibility Criteria

Inclusion

  • All patients should have BMI \> 30kg/m²
  • Present untreated diabetes mellitus type 2
  • Age between 19 and 50 years
  • Waist Circumference \> 80 cm

Exclusion

  • Renal, coronary vascular or peripheral, hematologic or hepatic disease
  • Presence of severe hypertriglyceridemia (\> 400mg/dl)
  • Smokers
  • Significant body mass loss (\> 5%) within the six months prior to the study

Key Trial Info

Start Date :

April 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2016

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01827280

Start Date

April 1 2013

End Date

November 1 2016

Last Update

May 31 2017

Active Locations (1)

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Laboratory for Clinical and Experimental Research on Vascular Biology

Rio de Janeiro, Brazil, 20550-900