Status:
COMPLETED
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Lead Sponsor:
GlaxoSmithKline
Conditions:
Dentine Hypersensitivity
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls. ...
Eligibility Criteria
Inclusion
- Participants with self-reported history of dentinal hypersensitivity lasting more than 6 months but not more than 10 years.
- Participants with minimum of 20 natural teeth.
- At screening, a minimum of two accessible teeth (incisors, canines, premolars) that meet all of the following criteria.
- Teeth showing signs of facial/cervical gingival recession and/or signs of erosion or abrasion.
- Teeth with Gingival Index score ≤1 and a clinical mobility of ≤1.
- Teeth that are determined to be sensitive by the subject following a 1 second air blast to the cervical margin.
Exclusion
- Presence of chronic debilitating disease which, in the opinion of the investigator, could affect study outcomes.
- Any condition which, in the opinion of the investigator, causes dry mouth.
- Tooth with evidence of current or recent caries, or reported treatment of decay in 12 months of screening.
- Participant using of a desensitising dentifrice within 6 weeks of screening
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
119 Patients enrolled
Trial Details
Trial ID
NCT01827670
Start Date
February 1 2013
End Date
May 1 2013
Last Update
January 26 2015
Active Locations (1)
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1
Salus Research, Inc.
Fort Wayne, Indiana, United States, 46825