Status:
COMPLETED
Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals
Lead Sponsor:
University of Reading
Collaborating Sponsors:
Alpro Foundation
Conditions:
Endothelial Function
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers. Specifically, the investigators plan to perform a randomised, doub...
Eligibility Criteria
Inclusion
- Male
- 18-40 years
- Healthy
- signed consent form
Exclusion
- Blood pressure \> 140/90 mmHg
- Had suffered a myocardial infarction or stroke
- Suffers from any blood-clotting disorder
- Suffers from any metabolic disorders (e.g. diabetes or any other endocrine or liver diseases)
- Any dietary restrictions or on a weight reducing diet
- Allergies or intolerances to any foods
- Smoker
- Heavy drinker (\>21 units per week)
- On any lipid-modifying medication
- On any blood pressure lowering medication
- On any medication affecting blood clotting
- Taking high dose fish oil supplements (greater then 1 g EPA and DHA per day) or high doses of antioxidant vitamins (greater then 800 μg vitamin A, 60 mg vitamin C, 10 mg vitamin E or 400 μg beta carotene)
- Taking probiotics, prebiotics, synbiotics, antibiotics or anti-inflammatory or blood lowering medication within a 2-month period prior to the study
- Planning on altering consumption of vitamin supplements/fish oil capsules during the course of the study
- Undertakes strenuous exercise \> 4 times per week for \> 1 hour per session
- Haemoglobin levels below reference range provided by the Royal Berkshire Hospital
Key Trial Info
Start Date :
May 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2012
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT01829542
Start Date
May 1 2012
End Date
October 1 2012
Last Update
April 11 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hugh Sinclair Unit of Human Nutrition
Reading, Berkshire, United Kingdom, RG6 6AP