Status:

UNKNOWN

Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy

Lead Sponsor:

Nanfang Hospital, Southern Medical University

Collaborating Sponsors:

Major Science and Technology Special Project of China Eleventh Five-year

Conditions:

Chronic Hepatitis B

Inadequate Response

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare the long-term efficacy and safety of entecavir 1.0 mg/d + adefovir 10 mg/d with entecavir 0.5 mg/d + adefovir 10 mg/d for chronic hepatitis B patients with inad...

Eligibility Criteria

Inclusion

  • Subjects who completed the 104-week Dragon study.
  • Subjects who are willing to participate the extension study.

Exclusion

  • Subjects who could not compliance with the protocol judged by investigators

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT01829685

Start Date

March 1 2013

Last Update

June 19 2014

Active Locations (16)

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Page 1 of 4 (16 locations)

1

Beijing Ditan Hospital

Beijing, Beijing Municipality, China

2

Beijing Friendship Hospital Attached To The Capital Medical University

Beijing, Beijing Municipality, China

3

Department of infectious disease, First Hospital of Peking University

Beijing, Beijing Municipality, China

4

People's Hospital Under Beijnig University

Beijing, Beijing Municipality, China