Status:
COMPLETED
Diurnal Variation in Hypertensive Stroke Patients
Lead Sponsor:
Hanmi Pharmaceutical Company Limited
Conditions:
Hypertension
Stroke
Eligibility:
All Genders
35-85 years
Phase:
PHASE4
Brief Summary
This study was conducted to evaluate and compare the effectiveness of Amodipin® (amlodipine camsylate) with that of Cozaar® (losartan potassium) in hypertensive patients with an acute ischemic stroke ...
Eligibility Criteria
Inclusion
- aged 35 to 85 years
- hypertensive patients who had an ischemic stroke
Exclusion
- patients aged below 35 years or above 86 years;
- patients who had a hemorrhagic stroke;
- patients whose systolic BP (SBP) was over 220 mmHg or whose diastolic BP (DBP) was above 120 mmHg during an acute phase, or whose SBP was over 180 mmHg or whose DBP was over 110 mmHg one week after their hospital visit;
- patients with secondary hypertension related to renovascular, endocrinologic, or pregnant conditions
- patients who went to bed in the middle of the day or very late at night; (6) patients who were using intravenous antico-agulants or thrombolytics;
- (7) patients with a severe stroke (NIH stroke scale \> 20); (8) patients who could not give their consent to investigators; (9) patients with severely impaired liver function (AST or ALT ≥ 100); (10) patients with severely impaired renal function (serum creatinine ≥ 2.0 mg/dL); (11) patients with cancer; (12) patients who were pregnant or lactating; (13) patients with other grave diseases such as hypertensive encephalopathy, aortic dissection, acute myocardial infarction, or severe congestive heart failure; and (14) patients who were allergic to the test or control drugs
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT01830517
Start Date
August 1 2007
End Date
February 1 2012
Last Update
April 12 2013
Active Locations (1)
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1
Boramae Medical Center
Boramae-ro 5-gil 20, Dongjak-gu, Seoul, South Korea, 156-707