Status:
COMPLETED
Renal Denervation in Patients With Chronic Kidney Disease
Lead Sponsor:
Saskatchewan Health Authority - Regina Area
Conditions:
Chronic Kidney Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
People with hypertension are at a higher risk for cardiovascular disease and death so it is important to lower blood pressure to normal levels as quickly as possible. Previous research has established...
Detailed Description
Study design and patients: This study will be conducted using a prospective, single-arm pre-/post-intervention design over 2 years. Fifty consecutive stage 3 and 4 CKD patients with resistant hyperte...
Eligibility Criteria
Inclusion
- Glomerular filtration rate: 60-15 mls/min as per the modified diet in renal disease formula (Stage 3 and 4 Chronic Kidney Disease)
- Daytime systolic blood pressure on ambulatory monitor ≥ 135 mm Hg while taking 3 or more anti-hypertensives including a diuretic on maximal dose OR ambulatory monitor systolic blood pressure is \<135 but taking 4 or more anti-hypertensives
- 18 years and above
- A minimum of 20 mm of length and 4 mm of diameter for renal arteries on CT renal angiogram or formal renal angiogram
Exclusion
- not suitable for renal denervation based on the Indications for Use
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT01832233
Start Date
February 1 2013
End Date
December 1 2015
Last Update
January 22 2020
Active Locations (1)
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1
Regina Qu'Appelle Health Region
Regina, Saskatchewan, Canada