Status:
COMPLETED
Coffee Polyphenols Antioxidants
Lead Sponsor:
Société des Produits Nestlé (SPN)
Conditions:
Healthy
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
Coffee is one of the most widely consumed beverages. It contains polyphenols (chlorogenic acids) and bioavailability of these bioactive compounds is now somewhat well understood. In addition, chloroge...
Detailed Description
This is an interventional study with a crossover randomized placebo-controlled double-blind design to assess the effect of regular consumption of coffee on oxidative stress compared to placebo.
Eligibility Criteria
Inclusion
- 20 - 70 years, male and female
- healthy
- BMI 19 - 29 kg/m2
- Coffee drinkers with an average consumption of 1-3 cups per day
- having given informed consent
Exclusion
- Intestinal or metabolic diseases / disorders such as diabetic, renal, hepatic, hypertension, pancreatic or ulcer- Have had a gastrointestinal surgery, except appendicectomy
- Difficulty to swallow
- Have a regular consumption of medication
- Have taken antibiotic therapy within the last 6 months
- Alcohol consumption \> 2 units a day
- Smokers (more than 5 cigarettes per day)
- Have given blood within the last 3 weeks
- Volunteers who cannot be expected to comply with treatment
- Currently participating or having participated in another clinical trial during the last 3 weeks
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01832662
Start Date
March 1 2011
End Date
June 1 2013
Last Update
April 21 2014
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