Status:
COMPLETED
Lactic Acidosis During and After Seizures
Lead Sponsor:
Stanford University
Conditions:
Epilepsy
Eligibility:
All Genders
18-75 years
Brief Summary
This project looks at the time course of lactic acid rise (if any) after seizures. Salivary and capillary lactic acid are tested. This type of measurement may be useful in signalling the occurrence or...
Detailed Description
Lactic acid is released from cells during seizures and elevates lactic acid levels in blood and saliva. The time course of this rise is unknown. If lactic acid rises within a few minutes of a seizure,...
Eligibility Criteria
Inclusion
- Age 18-75 inclusive.
- History of at least one generalized tonic-clonic (grand mal) seizure prior to enrollment in the study.
- Undergoing monitoring in the Stanford Epilepsy Monitoring Unit.
Exclusion
- Not pregnant.
- Inability to understand and sign the consent form.
- No known history of mitochondrial disease or other metabolic disorders expected to affect blood lactate.
- No known history of thrombophlebitis or excessive tendency to bleeding. Not on coumadin. Aspirin or anti-platelet agents are not an exclusion.
- No known peripheral vascular disease affecting blood circulation to the fingers.
- No painful peripheral neuropathy.
- No Raynaud's disease or phenomenon.
Key Trial Info
Start Date :
July 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01833247
Start Date
July 1 2012
End Date
December 1 2014
Last Update
May 5 2017
Active Locations (1)
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1
Stanford Hospital
Stanford, California, United States, 94305-5235