Status:
COMPLETED
Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy
Lead Sponsor:
Bezmialem Vakif University
Conditions:
Chronic Cholecystitis
Eligibility:
All Genders
20-60 years
Phase:
PHASE4
Brief Summary
Opioids may attenuate postoperative hyperalgesia and postoperative nausea and vomiting. Our hypothesis is: opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusio...
Detailed Description
Patients are randomly allocated into two groups to have either opioid-free anesthesia (Group DL) with dexmedetomidine (0.6 mg/kg loading, 0.3 mg/kg/h infusion), lidocaine (1.5 mg/kg loading, 2 mg/kg/h...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists I-II patients
- 20-60 years
Exclusion
- American Society of Anesthesiologists III and above patients
- BMI: 35 and above
- Hepatic, renal or cardiac insufficiency
- 2 degree Heart block and above
- Diabetes
- Psychiatric disease
- History of chronic pain
- Alcohol or drug abuse
- Allergy to any of a drug in the study groups
- Pregnant, breast-feeding or menstruating women
- Inability to use a patient-controlled analgesia device
- Any analgesic or antiemetic use in last 24 hours before anesthesia induction
- Any surgical complication that may affect the outcomes of the study (open surgery etc.)
Key Trial Info
Start Date :
June 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT01833819
Start Date
June 1 2012
End Date
April 1 2013
Last Update
November 13 2013
Active Locations (1)
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1
Bezmialem Vakif University Faculty of Medicine
Istanbul, Turkey (Türkiye), 34093