Status:

UNKNOWN

Patellar Tendinopathy - Effect of Training and Enhancement of the Collagen Synthesis by Insulin-like Growth Factor-I

Lead Sponsor:

Bispebjerg Hospital

Collaborating Sponsors:

The Danish Medical Research Council

Conditions:

Tendinopathy

Eligibility:

All Genders

18-50 years

Phase:

EARLY_PHASE1

Brief Summary

The purpose of the study is to test the hypothesis that stimulation of the synthesis of new structural tendon proteins combined with training improve the tendon structure in patients with chronic knee...

Detailed Description

Randomized controlled intervention study: 12 weeks intervention period with training and injections of saline or Insulin-Like growth factor I. One year follow-up

Eligibility Criteria

Inclusion

  • chronic patellar tendinopathy (\> 3 months)
  • anterior-posterior thickening of the tendon (1 mm compared to mid-tendon)
  • hypo-echoic area with enhanced vascularization

Exclusion

  • injection
  • corticosteroid injection within the last 12 months
  • Knee operation
  • Knee osteoarthritis
  • Diabetes
  • Smoking
  • Body mass index \>30

Key Trial Info

Start Date :

April 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01834989

Start Date

April 1 2013

End Date

December 1 2020

Last Update

July 29 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Institute of Sports Medicine, Copenhagen

Copenhagen, Denmark, 2400