Status:
COMPLETED
Regular Swimming, Vascular Function, and Arthritis
Lead Sponsor:
University of Texas at Austin
Conditions:
Osteoarthritis
Eligibility:
All Genders
40-90 years
Phase:
NA
Brief Summary
Hypothesis #1: The investigators hypothesize that both swimming training and cycling training will demonstrate significant improvements in endothelium-mediated vasodilation and central artery complian...
Detailed Description
Middle-aged and older men and women (40-90 years old) of all races and ethnic backgrounds will serve as subjects after obtaining their written, informed consent. All the subjects will have a radiologi...
Eligibility Criteria
Inclusion
- All the subjects will have a radiological diagnosis of osteoarthritis according to American College of Rheumatology criteria
- Subjects will be sedentary (i.e., no regular physical activity for at least the prior 1 year)
Exclusion
- Subjects with significant intima thickening,
- plaque formation, and/or characteristics of atherosclerosis.
- unstable cardiac or pulmonary diseases.
- joint replacement surgery in the previous year.
- intraarticular injection nor systemic steroids within previous 3 months.
- severe disabling co-morbidity that disallows receiving exercise therapy.
- excess alcohol use (\>21 drinks/week).
- unwillingness to perform exercise.
- fear of water.
- mental incapability
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT01836380
Start Date
January 1 2013
End Date
December 1 2014
Last Update
March 26 2015
Active Locations (1)
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1
The University of Texas at Austin
Austin, Texas, United States, 78712